Vol. 10 No. 3 (2024)
Papers

Supplementation with nutraceutical Calmina® (BuonaPET) improves anxiety status in shelter dogs: a pilot study

Viviana Orsola Giuliano
Department of Veterinary Medicine and Animal Production, University of Naples Federico II, Naples, Italy
Luigi Sacchettino
Department of Veterinary Medicine and Animal Production, University of Naples Federico II, Naples, Italy
Valentina Gazzano
Department of Veterinary Sciences, University of Pisa, Pisa, Italy
Davide Ciccarelli
Local Health Unit, Naples, Italy
Francesco Napolitano
Department of Veterinary Medicine and Animal Production, University of Naples Federico II, Naples, Italy CEINGE—Biotecnologie Avanzate Franco Salvatore, Naples, Italy
Danila d'Angelo
Department of Veterinary Medicine and Animal Production, University of Naples Federico II

Published 2025-08-28

Keywords

  • dog behavior,
  • stress,
  • serotonin,
  • cortisol,
  • human-dog relationship,
  • emotions
  • ...More
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Abstract

Shelter dogs may experience long-lasting stressful living conditions. As a result, veterinarians should use every tactic at their disposal to enhance these animals' comfort and well-being. In the present study, we enrolled dogs with an anxious profile, administered with a food supplement, based on fish protein hydrolysate (PEPTIDYSS®️), L-theanine, Griffonia simplicifolia, Lactobacillus Helveticus, Vitamin B6, Zinc and Magnesium. At the end of the 60-day treatment period, we documented for the first time a significant improvement in anxiety-based behaviors, evaluated by means an increase of problem-solving skills and interspecific sociability. Overall, our preliminary data shed light on the tantalizing role of Calmina®️ in animal shelter, with the purpose of improving the adoption chance for dogs, who experience emotional discomforts.